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2015

Pharmacokinetics of Bedaquiline in Cerebrospinal Fluid and Serum in Multidrug-Resistant Tuberculous Meningitis. Akkerman OW, Odish OF, Bolhuis MS, de Lange WC, Kremer HP, Luijckx GR, van der Werf TS, Alffenaar JW. Clin Infect Dis. 2015 Nov 3. [Epub ahead of print]  

Limited sampling strategies for therapeutic drug monitoring of amikacin and kanamycin in patients with multidrug-resistant tuberculosis. Dijkstra JA, van Altena R, Akkerman OW, de Lange WC, Proost JH, van der Werf TS, Kosterink JG, Alffenaar JW. Int J Antimicrob Agents. 2015 Sep;46(3):332-7

Determination of bedaquiline in human serum using liquid chromatography-tandem mass spectrometry. Alffenaar JW, Bolhuis M, van Hateren K, Sturkenboom M, Akkerman O, de Lange W, Greijdanus B, van der Werf T, Touw D. Antimicrob Agents Chemother. 2015 Sep;59(9):5675-80

Pharmacokinetic Modeling and Optimal Sampling Strategies for Therapeutic Drug Monitoring of Rifampin in Patients with Tuberculosis. Sturkenboom MG, Mulder LW, de Jager A, van Altena R, Aarnoutse RE, de Lange WC, Proost JH, Kosterink JG, van der Werf TS, Alffenaar JW.  Antimicrob Agents Chemother. 2015 Aug;59(8):4907-13

Evaluation of macrolides for possible use against multidrug-resistant Mycobacterium tuberculosis. van der Paardt AF, Wilffert B, Akkerman OW, de Lange WC, van Soolingen D, Sinha B, van der Werf TS, Kosterink JG, Alffenaar JW. Eur Respir J. 2015 Aug;46(2):444-55

Highly successful treatment outcome of multidrug-resistant tuberculosis in the Netherlands, 2000-2009. van Altena R, de Vries G, Haar CH, de Lange WC, Magis-Escurra C, van den Hof S, van Soolingen D, Boeree MJ, van der Werf TS. Int J Tuberc Lung Dis. 2015 Apr;19(4):406-12

A sore throat: tumour, tuberculosis or both? .van der Sar-van der Brugge S, Akkerman OW, van der Laan BF, de Lange WC, van der Werf TS. Ned Tijdschr Geneeskd. 2015;159:A8942

The role of therapeutic drug monitoring in individualised drug dosage and exposure measurement in tuberculosis and HIV co-infection. Daskapan A, de Lange WC, Akkerman OW, Kosterink JG, van der Werf TS, Stienstra Y, Alffenaar JW. Eur Respir J. 2015 Feb;45(2):569-71

Breakpoints and drug exposure are inevitably closely linked. Alffenaar JW, Akkerman OW, Bolhuis MS, Boeree MJ, de Lange WC, van der Werf TS. Antimicrob Agents Chemother. 2015 Feb;59(2):1384

2014

Raltegravir and rifampicin in patients with HIV and tuberculosis. Klis S, Daskapan A, Akkerman OW, Alffenaar JW, Stienstra Y. Lancet Infect Dis. 2014 Nov;14(11):1046-7.

Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement.  Lange C, Abubakar I, Alffenaar JW, Bothamley G, Caminero JA, Carvalho AC, Chang KC, Codecasa L, Correia A, Crudu V, Davies P, Dedicoat M, Drobniewski F, Duarte R, Ehlers C, Erkens C, Goletti D, Günther G, Ibraim E, Kampmann B, Kuksa L, de Lange W, van Leth F, van Lunzen J, Matteelli A, Menzies D, Monedero I, Richter E, Rüsch-Gerdes S, Sandgren A, Scardigli A, Skrahina A, Tortoli E, Volchenkov G, Wagner D, van der Werf MJ, Williams B, Yew WW, Zellweger JP, Cirillo DM; TBNET. Eur Respir J. 2014 Jul;44(1):23-63.

Optimization of standard in-house 24-locus variable-number tandem-repeat typing for Mycobacterium tuberculosis and its direct application to clinical material. de Beer JL, Akkerman OW, Schürch AC, Mulder A, van der Werf TS, van der Zanden AG, van Ingen J, van Soolingen D. J Clin Microbiol. 2014 May;52(5):1338-42.

Potential antimicrobial agents for the treatment of multidrug-resistant tuberculosis. Alsaad N, Wilffert B, van Altena R, de Lange WC, van der Werf TS, Kosterink JG, Alffenaar JW. Eur Respir J. 2014 Mar;43(3):884-97


2013

Drug concentration in lung tissue in multidrug-resistant tuberculosis. Akkerman OW, van Altena R, Klinkenberg T, Brouwers AH, Bongaerts AH, van der Werf TS, Alffenaar JW. Eur Respir J. 2013 Dec;42(6):1750-2.

Clinical validation of the analysis of linezolid and clarithromycin in oral fluid of patients with multidrug-resistant tuberculosis. Bolhuis MS, van Altena R, van Hateren K, de Lange WC, Greijdanus B, Uges DR, Kosterink JG, van der Werf TS, Alffenaar JW. Antimicrob Agents Chemother. 2013 Aug;57(8):3676-80

Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients. Bolhuis MS, van Altena R, van Soolingen D, de Lange WC, Uges DR, van der Werf TS, Kosterink JG, Alffenaar JW. Eur Respir J. 2013 Dec;42(6):1614-21

Evaluation of co-trimoxazole in the treatment of multidrug-resistant tuberculosis. Alsaad N, van Altena R, Pranger AD, van Soolingen D, de Lange WC, van der Werf TS, Kosterink JG, Alffenaar JW. Eur Respir J. 2013 Aug;42(2):504-12

Comparison of 14 molecular assays for detection of Mycobacterium tuberculosis complex in bronchoalveolar lavage fluid. Akkerman OW, van der Werf TS, de Boer M, de Beer JL, Rahim Z, Rossen JW, van Soolingen D, Kerstjens HA, van der Zanden AG. J Clin Microbiol. 2013 Nov;51(11):3505-11