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Blood lipids-related dietary patterns derived from reduced rank regression are associated with incident type 2 diabetes

06 July 2021

​Ming-Jie Duan, Louise H. Dekker, Juan-Jesus Carrero, Gerjan Navis

Blood lipids play a critical role in the pathogenesis of type 2 diabetes, and they are closely related to dietary factors. However, the associations between blood lipids-related dietary patterns and risk of type 2 diabetes are not fully clear. In this study, we derived dietary patterns that explained variation in blood lipids and we found that these dietary patterns were significantly associated with incident type 2 diabetes in a large population-based sample. Our findings support the hypothesis that dietary factors increase the risk of type 2 diabetes through altered blood lipid profiles. Our results provide important insights in optimizing blood lipids for diabetes prevention through dietary approaches.

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