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Involving patients in the assessment and evaluation of medication treatment

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Title:   Involving patients in the assessment and evaluation of medication treatment
Investigator :  Sieta de Vries
Supervisor :  Petra Denig
Promotores :  Petra Denig, Floor Haaijer-Ruskamp, Dick de Zeeuw
Summary:  The first aim of the project is to develop a patient-oriented risk assessment instrument for addressing common, non-serious adverse drug events, and to evaluate the feasibility of implementing the method in trials and post-marketing surveillance. A patient-reported Adverse Drug Event (ADE) questionnaire will be developed and its reliability and validity will be tested in patients with type 2 diabetes mellitus. Qualitative and cross-sectional studies will be used to assess this aim.
The second aim of is to assess the influence of patients’ medication beliefs, age and life-expectancy on treatment preferences and decisions for preventive medication. A discrete choice experiment will be conducted among patients with type 2 diabetes mellitus.
Financing: 3e GS, TI Pharma Escher Project (2.7), 1e GS, SHARE
Start :  1-1-2010
End : 1-12-2014

 

Projects
The use of a multiple parameter response efficacy score to predict the effect of a drug on hard renal and cardiovascular
Diabetes Mellitus Treatment for Renal Insufficiency Consortium (DIAMETRIC) database 
System biology approach for discovery of biomarkers of renal disease progressioni in diabetes (SysKid)
PROVALID – prospective multinational cohort study in patients with type 2 diabetes treated in primary care
Vitamin-D deficiency as a risk marker for renal and CV complications in the general population
A novel approach of personalized medicine: considering multiple effects of a single drug
Optimal hard endpoints in clinical trials of renal disease progression
Albuminuria as surrogate endpoint in clinical trials
Individual therapy response to a sodium-glucose transport inhibitor
Involving patients in the assessment and evaluation of medication treatment
Groningen Initiative to Analyse Type-2 diabetes Treatment ( GIANTT )
The role of medication adherence in predicting treatment response and estimating cost-effectiveness of statin treatment
Pharmacogenetics and response to treatment of oral antidiabetics
Quality of prescribing: patient specific indicators that predict better outcomes in diabetes patients
Quality assessment of pharmacotherapy in patients with chronic kidney disease
Cost effectiveness of ACEi and ARBs on renal failure in diabetes patients
Drug information and risk communication in Africa
Regulatory Science Projects