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Publications 2017

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  1. Aardema H, Nannan Panday P, Wessels M, van Hateren K, Dieperink W, Kosterink JGW, Alffenaar JW, Zijlstra JG. Target attainment with continuous dosing of piperacillin/tazobactam in critical illness: a prospective observational study. Int J Antimicrob Agents. 2017 Jul;50(1):68-73. ​
  2. Alffenaar JC, Akkerman OW, Anthony RM, Tiberi S, Heysell S, Grobusch MP, Cobelens FG, Van Soolingen D. Individualizing management of extensively drug-resistant tuberculosis: diagnostics, treatment, and biomarkers. Expert Rev Anti Infect Ther. 2017 Jan;15(1):11-21. Epub 2016 Oct 24. PubMed PMID: 27762157.
  3. Alffenaar JC, Migliori GB, Gumbo T. Multidrug-resistant tuberculosis: pharmacokinetic and pharmacodynamic science. Lancet Infect Dis. 2017 Sep;17(9):898. doi: 10.1016/S1473-3099(17)30449-8. PubMed PMID: 28845791.
  4. Alffenaar JC, Tiberi S, Verbeeck RK, Heysell SK, Grobusch MP. Therapeutic Drug Monitoring in Tuberculosis: Practical Application for Physicians. Clin Infect Dis. 2017 Jan 1;64(1):104-105. Epub 2016 Oct 6. PubMed PMID: 27789609.
  5. Alffenaar JC, van Ingen J. Treatment of Mycobacterium avium-intracellulare complex: a great leap forward. J Antimicrob Chemother. 2017 Sep 1;72(suppl_2):i1-i2. doi: 10.1093/jac/dkx310. PubMed PMID: 28922812.
  6. Alvarez-Jimenez R, Baakman AC, Stevens J, Goulooze SC, Hart EP, Rissmann R, van Gerven JM, Groeneveld GJ. Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation. J Psychopharmacol. 2017  Feb;31(2):192-203. doi: 10.1177/0269881116681417. Epub 2016 Dec 9. PubMed PMID: 27927703.
  7. Baakman AC, Alvarez-Jimenez R, Rissmann R, Klaassen ES, Stevens J, Goulooze SC, den Burger JCG, Swart EL, van Gerven JMA, Groeneveld GJ. An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine. Br J Clin Pharmacol. 2017  Aug;83(8):1676-1687. doi: 10.1111/bcp.13268. Epub 2017 Apr 8. PubMed PMID: 28217868; PubMed Central PMCID: PMC5510063.
  8. Bahar MA, Hak E, Bos JHJ, Borgsteede SD, Wilffert B. The burden and management of cytochrome P450 2D6 (CYP2D6)-mediated drug-drug interaction (DDI): co-medication of metoprolol and paroxetine or fluoxetine in the elderly. Pharmacoepidemiol Drug Saf. 2017 Jul;26(7):752-765. doi: 10.1002/pds.4200. Epub 2017 Mar 26. PubMed PMID: 28345306.
  9. Bahar MA, Setiawan D, Hak E, Wilffert B. Pharmacogenetics of drug-drug interaction and drug-drug-gene interaction: a systematic review on CYP2C9, CYP2C19 and CYP2D6. Pharmacogenomics. 2017 May;18(7):701-739. doi: 10.2217/pgs-2017-0194. Epub 2017 May 8. PubMed PMID: 28480783.
  10. Baigent C, Herrington WG, Coresh J, Landray MJ, Levin A, Perkovic V, Pfeffer MA, Rossing P, Walsh M, Wanner C, Wheeler DC, Winkelmayer WC, McMurray JJV; KDIGO Controversies Conference on Challenges in the Conduct of Clinical Trials in Nephrology Conference Participants. Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease-Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2017 Aug;92(2):297-305. doi: 10.1016/j.kint.2017.04.019. PubMed PMID: 28709600.
  11. Bensch F, Lamberts LE, Smeenk MM, Jorritsma-Smit A, Lub-de Hooge MN, Terwisscha van Scheltinga AGT, de Jong JR, Gietema JA, Schröder CP, Thomas M, Jacob W, Abiraj K, Adessi C, Meneses-Lorente G, James I, Weisser M, Brouwers AH, de Vries EGE. (89)Zr-Lumretuzumab PET Imaging before and during HER3 Antibody Lumretuzumab Treatment in Patients with Solid Tumors. Clin Cancer Res. 2017 Oct 15;23(20):6128-6137. doi: 10.1158/1078-0432.CCR-17-0311. Epub 2017 Jul 21. PubMed PMID: 28733442; PubMed Central PMCID: PMC5642894.
  12. Berhe DF, Taxis K, Haaijer-Ruskamp FM, Mulugeta A, Mengistu YT, Burgerhof JGM, Mol PGM. Impact of adverse drug events and treatment satisfaction on patient adherence with antihypertensive medication - a study in ambulatory patients. Br J Clin Pharmacol. 2017 Sep;83(9):2107-2117. doi: 10.1111/bcp.13312. Epub 2017 Jun 15. PubMed PMID: 28429533; PubMed Central PMCID: PMC5555859.
  13. Berhe DF, Taxis K, Haaijer-Ruskamp FM, Mulugeta A, Mengistu YT, Mol PGM. Hypertension treatment practices and its determinants among ambulatory patients: retrospective cohort study in Ethiopia. BMJ Open. 2017 Aug 3;7(8):e015743. doi:10.1136/bmjopen-2016-015743. PubMed PMID: 28775184.
  14. Bidadkosh A, Lambooy SPH, Heerspink HJ, Pena MJ, Henning RH, Buikema H, Deelman LE. Predictive Properties of Biomarkers GDF-15, NTproBNP, and hs-TnT for Morbidity and Mortality in Patients With Type 2 Diabetes With Nephropathy. Diabetes Care. 2017 Jun;40(6):784-792. doi: 10.2337/dc16-2175. Epub 2017 Mar 24.  PubMed PMID: 28341782.
  15. Boonstra JM, van der Elst KC, Veringa A, Jongedijk EM, Brüggemann RJ, Koster  RA, Kampinga GA, Kosterink JG, van der Werf TS, Zijlstra JG, Touw DJ, Alffenaar JWC. Pharmacokinetic Properties of Micafungin in Critically Ill Patients Diagnosed with Invasive Candidiasis. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01398-17. doi: 10.1128/AAC.01398-17. Print 2017 Dec. PubMed PMID: 28971861.
  16. Borisov SE, Dheda K, Enwerem M, Romero Leyet R, D'Ambrosio L, Centis R, Sotgiu G, Tiberi S, Alffenaar JW, Maryandyshev A, Belilovski E, Ganatra S, Skrahina A, Akkerman O, Aleksa A, Amale R, Artsukevich J, Bruchfeld J, Caminero JA, Carpena Martinez I, Codecasa L, Dalcolmo M, Denholm J, Douglas P, Duarte R, Esmail A, Fadul M, Filippov A, Davies Forsman L, Gaga M, Garcia-Fuertes JA, García-García JM, Gualano G, Jonsson J, Kunst H, Lau JS, Lazaro Mastrapa B, Teran Troya JL, Manga S, Manika K, González Montaner P, Mullerpattan J, Oelofse S, Ortelli M, Palmero DJ, Palmieri F, Papalia A, Papavasileiou A, Payen MC, Pontali E, Robalo Cordeiro C, Saderi L, Sadutshang TD, Sanukevich T, Solodovnikova V, Spanevello A, Topgyal S, Toscanini F, Tramontana AR, Udwadia ZF, Viggiani P, White V, Zumla A, Migliori GB. Effectiveness and safety of bedaquiline-containing regimens in the treatment of MDR- and XDR-TB: a multicentre study. Eur Respir J. 2017 May 21;49(5). pii: 1700387. doi: 10.1183/13993003.00387-2017. Print 2017 May. PubMed PMID: 28529205.
  17. Bouma HR, Schreuder RM. An unexpected cause of nausea and vomiting in a patient with metastasised lung cancer. Neth J Med. 2017 Jun;75(5):215. PubMed PMID: 28653948.
  18. Caño-Muñiz S, Anthony R, Niemann S, Alffenaar JC. New Approaches and Therapeutic Options for Mycobacterium tuberculosis in a Dormant State. Clin Microbiol Rev. 2017 Nov 29;31(1). pii: e00060-17. doi: 10.1128/CMR.00060-17.Print 2018 Jan. Review. PubMed PMID: 29187395.
  19. Charytan DM, Solomon SD, Ivanovich P, Remuzzi G, Cooper ME, McGill JB, Parving HH, Parfrey P, Singh AK, Burdmann EA, Levey AS, de Zeeuw D, Eckardt KU, McMurray JJV, Claggett B, Lewis EF, Pfeffer MA. ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type 2 Diabetic Patients With CKD. Am J Kidney Dis. 2017 Oct;70(4):522-531. doi: 10.1053/j.ajkd.2017.04.018. Epub 2017 Jun 7. PubMed PMID: 28599901.
  20. Cherney D, Perkins BA, Lytvyn Y, Heerspink H, Rodríguez-Ortiz ME, Mischak H. The effect of sodium/glucose cotransporter 2 (SGLT2) inhibition on the urinary proteome. PLoS One. 2017 Oct 30;12(10):e0186910. doi: 10.1371/journal.pone.0186910. eCollection 2017. PubMed PMID: 29084249; PubMed Central PMCID: PMC5662219.
  21. Cikova A, Vavrincova-Yaghi D, Vavrinec P, Dobisova A, Gebhardtova A, Flassikova Z, Seelen MA, Henning RH, Yaghi A. Gastrointestinal tuberculosis following renal transplantation accompanied with septic shock and acute respiratory distress syndrome: a survival case presentation. BMC Gastroenterol. 2017 Nov 28;17(1):131. doi: 10.1186/s12876-017-0695-5. PubMed PMID: 29179699.
  22. Cowie MR, Filippatos GS, Alonso Garcia MLA, Anker SD, Baczynska A, Bloomfield DM, Borentain M, Bruins Slot K, Cronin M, Doevendans PA, El-Gazayerly A, Gimpelewicz C, Honarpour N, Janmohamed S, Janssen H, Kim AM, Lautsch D, Laws I, Lefkowitz M, Lopez-Sendon J, Lyon AR, Malik FI, McMurray JJV, Metra M, Figueroa Perez S, Pfeffer MA, Pocock SJ, Ponikowski P, Prasad K, Richard-Lordereau I, Roessig L, Rosano GMC, Sherman W, Stough WG, Swedberg K, Tyl B, Zannad F, Boulton C, De Graeff P. New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment. Eur J Heart Fail. 2017 Jun;19(6):718-727. doi: 10.1002/ejhf.809. Epub 2017 Mar 27. Review. PubMed PMID:  28345190.
  23. Daskapan A, Dijkema D, de Weerd DA, Bierman WFW, Kosterink JGW, van der Werf TS, Alffenaar JC, Stienstra Y. Food intake and darunavir plasma concentrations in people living with HIV in an outpatient setting. Br J Clin Pharmacol. 2017 Oct;83(10):2325-2329. doi: 10.1111/bcp.13366. Epub 2017 Aug 1. PubMed PMID: 28686287; PubMed Central PMCID: PMC5595942.
  24. Daud AN, Bergman JE, Oktora MP, Kerstjens-Frederikse WS, Groen H, Bos JH, Hak E, Wilffert B. Maternal use of drug substrates of placental transporters and the effect of transporter-mediated drug interactions on the risk of congenital anomalies. PLoS One. 2017 Mar 13;12(3):e0173530. doi:10.1371/journal.pone.0173530. eCollection 2017. PubMed PMID: 28288183; PubMed Central PMCID: PMC5348032.
  25. Daud ANA, Bergsma EL, Bergman JEH, De Walle HEK, Kerstjens-Frederikse WS, Bijker BJ, Hak E, Wilffert B. Knowledge and attitude regarding pharmacogenetics among formerly pregnant women in the Netherlands and their interest in pharmacogenetic research. BMC Pregnancy Childbirth. 2017 Apr 14;17(1):120. doi: 10.1186/s12884-017-1290-z. PubMed PMID: 28410576.
  26. Davies Forsman L, Bruchfeld J, Alffenaar JC. Therapeutic drug monitoring to prevent acquired drug resistance of fluoroquinolones in the treatment of tuberculosis. Eur Respir J. 2017 Apr 26;49(4). pii: 1700173. doi: 10.1183/13993003.00173-2017. Print 2017 Apr. PubMed PMID: 28446561.
  27. de Boer SA, Heerspink HJL, Juárez Orozco LE, van Roon AM, Kamphuisen PW, Smit  AJ, Slart RHJA, Lefrandt JD, Mulder DJ. Effect of linagliptin on pulse wave velocity in early type 2 diabetes: A randomized, double-blind, controlled 26-week trial (RELEASE). Diabetes Obes Metab. 2017 Aug;19(8):1147-1154. doi: 10.1111/dom.12925. Epub 2017 Apr 10. PubMed PMID: 28244635.
  28. de Boer SA, Heerspink HJ, Lefrandt JD, Hovinga-de Boer MC, van Roon AM, Juárez Orozco LE, Glaudemans AW, Kamphuisen PW, Slart RH, Mulder DJ. Effect of Linagliptin on Arterial (18)F-Fluorodeoxyglucose Positron Emission Tomography Uptake: A Randomized Controlled Trial (RELEASE). J Am Coll Cardiol. 2017 Feb 28;69(8):1097-1098. doi: 10.1016/j.jacc.2016.12.018. PubMed PMID: 28231936.
  29. de Vries LV, de Jong WHA, Touw DJ, Berger SP, Navis G, Kema IP, Bakker SJL. Twenty-four hour urinary cortisol excretion and the metabolic syndrome in prednisolone-treated renal transplant recipients. Steroids. 2017 Nov;127:31-39. doi: 10.1016/j.steroids.2017.09.001. Epub 2017 Sep 8. PubMed PMID: 28893559.
  30. de Vries ST, van der Sar MJM, Cupelli A, Baldelli I, Coleman AM, Montero D, Šipić I, Andrić A, Wennberg A, Ahlqvist-Rastad J, Denig P, Mol PGM; SCOPE Work Package 6. Communication on Safety of Medicines in Europe: Current Practices and  General Practitioners' Awareness and Preferences. Drug Saf. 2017 Aug;40(8):729-742. doi: 10.1007/s40264-017-0535-0. PubMed PMID: 28540672; PubMed  Central PMCID: PMC5519651.
  31. de Vries ST, Wong L, Sutcliffe A, Houÿez F, Ruiz CL, Mol PG; IMI Web-RADR Work Package 3b Consortium. Factors Influencing the Use of a Mobile App for Reporting Adverse Drug Reactions and Receiving Safety Information: A Qualitative Study. Drug Saf. 2017 May;40(5):443-455. doi: 10.1007/s40264-016-0494-x. PubMed PMID: 28035492; PubMed Central PMCID: PMC5384960.
  32. Dekkers BGJ, Eck RJ, Ter Maaten JC, Touw DJ. An acute oral intoxication with  haloperidol decanoate. Am J Emerg Med. 2017 Sep;35(9):1387.e1-1387.e2. doi: 10.1016/j.ajem.2017.07.013. Epub 2017 Jul 5. PubMed PMID: 28705742.
  33. Dijkmans AC, Kuiper SG, Burggraaf J, Mouton JW, Wilms EB, Touw DJ, Stevens J, van Nieuwkoop C, Kamerling IMC. [Fosfomycin, an old antibiotic with new possibilities]. Ned Tijdschr Geneeskd. 2017;161(0):D973. Dutch. PubMed PMID: 28612692.
  34. Dijkmans AC, Zacarías NVO, Burggraaf J, Mouton JW, Wilms EB, van Nieuwkoop C, Touw DJ, Stevens J, Kamerling IMC. Fosfomycin: Pharmacological, Clinical and Future Perspectives. Antibiotics (Basel). 2017 Oct 31;6(4). pii: E24. doi: 10.3390/antibiotics6040024. Review. PubMed PMID: 29088073.
  35. Dijkstra A, Touw DJ, van Rheenen PF. Simple Urine Test to Evaluate Adherence to Oral 5-ASA in Teenagers With Ulcerative Colitis: Proof of Concept. J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):416-419. doi: 10.1097/MPG.0000000000001541. PubMed PMID: 28169975.
  36. Doesburg F, Cnossen F, Dieperink W, Bult W, de Smet AM, Touw DJ, Nijsten MW. Improved usability of a multi-infusion setup using a centralized control interface: A task-based usability test. PLoS One. 2017 Aug 11;12(8):e0183104. doi: 10.1371/journal.pone.0183104. eCollection 2017. PubMed PMID: 28800617; PubMed Central PMCID: PMC5553772.
  37. Dugbartey GJ, Hardenberg MC, Kok WF, Boerema AS, Carey HV, Staples JF, Henning RH, Bouma HR. Renal Mitochondrial Response to Low Temperature in Non-Hibernating  and Hibernating Species. Antioxid Redox Signal. 2017 Sep 20;27(9):599-617. doi: 10.1089/ars.2016.6705. Epub 2017 Apr 26. PubMed PMID: 28322600.
  38. Duong JK, Kroonen MYAM, Kumar SS, Heerspink HL, Kirkpatrick CM, Graham GG, Williams KM, Day RO. A dosing algorithm for metformin based on the relationships  between exposure and renal clearance of metformin in patients with varying degrees of kidney function. Eur J Clin Pharmacol. 2017 Aug;73(8):981-990. doi: 10.1007/s00228-017-2251-1. Epub 2017 Apr 28. PubMed PMID: 28451709.
  39. Eisenga MF, Dullaart RPF, Berger SP, Touw DJ, Bakker SJL, Gaillard CAJM. Urinary prednisolone excretion is a determinant of serum hepcidin levels in renal transplant recipients. Am J Hematol. 2017 Aug;92(8):E173-E175. doi: 10.1002/ajh.24785. Epub 2017 Jun 9. PubMed PMID: 28494514; PubMed Central PMCID: PMC5518224.
  40. Fenten MG, Bakker SM, Touw DJ, van den Bemt BJ, Scheffer GJ, Heesterbeek PJ, Stienstra R. Pharmacokinetics of 400 mg ropivacaine after periarticular local infiltration analgesia for total knee arthroplasty. Acta Anaesthesiol Scand. 2017 Mar;61(3):338-345. doi: 10.1111/aas.12849. Epub 2017 Jan 9. PubMed PMID: 28066882.
  41. Filippatos GS, de Graeff P, Bax JJ, Borg J-J, Cleland JGF, Dargie HJ et al. Independent academic Data Monitoring Committees for clinical trials in cardiovascular and cardiometabolic diseases. European Journal of Heart Failure. 2017 Apr;19(4):449-456. Available from, DOI: 10.1002/ej​hf.761
  42. Forsman, LD, Bruchfeld, J & Alffenaar, J-WC 2017, 'Therapeutic drug monitoring to prevent acquired drug resistance of fluoroquinolones in the treatment of tuberculosis' European Respiratory Journal, vol 49, no. 4. DOI: 10.1183/13993003.00173-2017
  43. Gabb GM, Mol PGM, Arnolda LF. A personalised or procrustean approach to treating hypertension? Lancet. 2017 Jul 1;390(10089):26-27. doi: 10.1016/S0140-6736(17)31597-0. PubMed PMID: 28677555.
  44. Gant CM, Laverman GD, Vogt L, Slagman MCJ, Heerspink HJL, Waanders F, Hemmelder MH, Navis G; Holland Nephrology Study (HONEST) Network. Renoprotective RAAS inhibition does not affect the association between worse renal function and higher plasma aldosterone levels. BMC Nephrol. 2017 Dec 20;18(1):370. doi:10.1186/s12882-017-0789-x. PubMed PMID: 29262813; PubMed Central PMCID: PMC5738866.
  45. GBD 2015 Chronic Respiratory Disease Collaborators. Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Respir Med. 2017 Sep;5(9):691-706. doi: 10.1016/S2213-2600(17)30293-X. Epub 2017 Aug 1. PubMed PMID: 28822787; PubMed Central PMCID: PMC5573769.
  46. GBD 2015 Healthcare Access and Quality Collaborators Healthcare Access and Quality Index based on mortality from causes amenable to personal healthcare in 195 countries and territories, 1990–2015: a novel analysis from the Global Burden of Disease Study 2015 The Lancet 2017; 390(10091):231-266.
  47. GBD 2016 Causes of Death Collaborators. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for  the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1151-1210. doi: 10.1016/S0140-6736(17)32152-9. PubMed PMID: 28919116.
  48. GBD 2016 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1260-1344. doi: 10.1016/S0140-6736(17)32130-X. PubMed PMID: 28919118.
  49. GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1211-1259. doi: 10.1016/S0140-6736(17)32154-2. PubMed PMID: 28919117.
  50. GBD 2016 Mortality Collaborators. Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1084-1150. doi: 10.1016/S0140-6736(17)31833-0. PubMed PMID: 28919115.
  51. GBD 2016 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1345-1422. doi: 10.1016/S0140-6736(17)32366-8. PubMed PMID: 28919119.
  52. GBD 2016 SDG Collaborators. Measuring progress and projecting attainment on the basis of past trends of the health-related Sustainable Development Goals in 188 countries: an analysis from the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1423-1459. doi: 10.1016/S0140-6736(17)32336-X. Epub 2017 Sep 12. PubMed PMID: 28916366.
  53. GBD Diabetes collaborators Diabetes mellitus and chronic kidney disease in the Eastern Mediterranean Region: Findings from the 2015 Global Burden of Disease study International Journal of Public Health 2017; doi: 10.1007/s00038-017-1014-1
  54. Geers LM, Cohen D, Wehkamp LM, van Hateren K, Koster RA, Fedorenko OY, Semke AV, Bokhan N, Ivanova SA, Kosterink JGW, Loonen AJM, Touw DJ. Dried Blood Spot Analysis for Therapeutic Drug Monitoring of Clozapine. J Clin Psychiatry. 2017 Nov/Dec;78(9):e1211-e1218. doi: 10.4088/JCP.16m11164. PubMed PMID: 29068609.
  55. Gomes A, Glaudemans AW, Touw DJ, van Melle JP, Willems TP, Maass AH, Natour E, Prakken NH, Borra RJ, van Geel PP, Slart RH, van Assen S, Sinha B. Diagnostic value of imaging in infective endocarditis: a systematic review. Lancet Infect Dis. 2017 Jan;17(1):e1-e14. doi: 10.1016/S1473-3099(16)30141-4. Epub 2016 Oct 18. Review. PubMed PMID: 27746163.
  56. Gomes A, van der Wijk L, Proost JH, Sinha B, Touw DJ. Pharmacokinetic modeling of gentamicin in treatment of infective endocarditis: Model development and validation of existing models. PLoS One. 2017 May 5;12(5):e0177324. doi: 10.1371/journal.pone.0177324. eCollection 2017. PubMed PMID: 28475651; PubMed Central PMCID: PMC5419648.
  57. Hajmousa G, Vogelaar P, Brouwer LA, van der Graaf AC, Henning RH, Krenning G. The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells. Biomaterials. 2017 Mar;119:43-52. doi: 10.1016/j.biomaterials.2016.12.008. Epub 2016 Dec 9. PubMed PMID: 28006657.
  58. Hamidi Shishavan M, Henning RH, van Buiten A, Goris M, Deelman LE, Buikema H. Metformin Improves Endothelial Function and Reduces Blood Pressure in Diabetic Spontaneously Hypertensive Rats Independent from Glycemia Control: Comparison to Vildagliptin. Sci Rep. 2017 Sep 8;7(1):10975. doi: 10.1038/s41598-017-11430-7. PubMed PMID: 28887562; PubMed Central PMCID: PMC5591199.
  59. Hartmans E, Linssen MD, Sikkens C, Levens A, Witjes MJH, van Dam GM, Nagengast WB. Tyrosine kinase inhibitor induced growth factor receptor upregulation enhances the efficacy of near-infrared targeted photodynamic therapy in esophageal adenocarcinoma cell lines. Oncotarget. 2017 May 2;8(18):29846-29856. doi: 10.18632/oncotarget.16165. PubMed PMID: 28415738; PubMed Central PMCID: PMC5444708.
  60. Heerspink HJ, Desai M, Jardine M, Balis D, Meininger G, Perkovic V. Canagliflozin Slows Progression of Renal Function Decline Independently of Glycemic Effects. J Am Soc Nephrol. 2017 Jan;28(1):368-375. doi: 10.1681/ASN.2016030278. Epub 2016 Aug 18. PubMed PMID: 27539604; PubMed Central PMCID: PMC5198289.
  61. Heerspink HJ, Makino H, Andress D, Brennan JJ, Correa-Rotter R, Coll B, Davis JW, Idler K, Kohan DE, Liu M, Perkovic V, Remuzzi G, Tobe SW, Toto R, Parving HH, de Zeeuw D. Comparison of exposure response relationship of atrasentan between North American and Asian populations. Diabetes Obes Metab. 2017 Apr;19(4):545-552. doi: 10.1111/dom.12851. Epub 2017 Jan 27. PubMed PMID: 27981738.
  62. Hendriks KDW, Lupi E, Hardenberg MC, Hoogstra-Berends F, Deelman LE, Henning RH. Differences in mitochondrial function and morphology during cooling and rewarming between hibernator and non-hibernator derived kidney epithelial cells. Sci Rep. 2017 Nov 14;7(1):15482. doi: 10.1038/s41598-017-15606-z. PubMed PMID: 29138454; PubMed Central PMCID: PMC5686174.
  63. Henning RH, Brundel BJJM. Proteostasis in cardiac health and disease. Nat Rev Cardiol. 2017 Nov;14(11):637-653. doi: 10.1038/nrcardio.2017.89. Epub 2017 Jun 29. Review. PubMed PMID: 28660894.
  64. Heuker M, Sijbesma JWA, Suárez RA, de Jong JR, Boersma HH, Luurtsema G, Elsinga PH, Glaudemans AWJM, van Dam GM, van Dijl JM, Slart RHJA, van Oosten M. In vitro imaging of bacteria using (18)F-fluorodeoxyglucose micro positron emission tomography. Sci Rep. 2017 Jul 10;7(1):4973. doi: 10.1038/s41598-017-05403-z. PubMed PMID: 28694519; PubMed Central PMCID: PMC5504029.
  65. Ivanova SA, Osmanova DZ, Boiko AS, Pozhidaev IV, Freidin MB, Fedorenko OY, Semke AV, Bokhan NA, Kornetova EG, Rakhmazova LD, Wilffert B, Loonen AJ. Prolactin gene polymorphism (-1149 G/T) is associated with hyperprolactinemia in patients with schizophrenia treated with antipsychotics. Schizophr Res. 2017 Apr;182:110-114. doi: 10.1016/j.schres.2016.10.029. Epub 2016 Oct 21. PubMed PMID: 27776952.
  66. Ivanova SA, Osmanova DZ, Freidin MB, Fedorenko OY, Boiko AS, Pozhidaev IV, Semke AV, Bokhan NA, Agarkov AA, Wilffert B, Loonen AJ. Identification of 5-hydroxytryptamine receptor gene polymorphisms modulating hyperprolactinaemia in antipsychotic drug-treated patients with schizophrenia. World J Biol Psychiatry.  2017 Apr;18(3):239-246. doi: 10.1080/15622975.2016.1224926. Epub 2016 Sep 22. PubMed PMID: 27654063.
  67. Jager NG, Zandvliet AS, Touw DJ, Penne EL. Optimization of anti-infective dosing regimens during online haemodiafiltration. Clin Kidney J. 2017 Apr;10(2):282-290. doi: 10.1093/ckj/sfx009. Epub 2017 Mar 29. PubMed PMID: 28396747; PubMed Central PMCID: PMC5381234.
  68. Jonker CJ, van den Berg HM, Kwa MSG, Hoes AW, Mol PGM. Registries supporting new drug applications. Pharmacoepidemiol Drug Saf. 2017 Dec;26(12):1451-1457. doi: 10.1002/pds.4332. Epub 2017 Oct 6. PubMed PMID: 28983992; PubMed Central PMCID: PMC5725674.
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