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12th Pharmacometrics Network Benelux Meeting and pre-symposium workshop “Advancement in Pharmacometric Tools”


We are happy to invite you to the 12th Pharmacometrics Network Benelux Meeting and pre-symposium workshop. This initiative aims to connect pharmacometricians in the Benelux (Belgium, Netherlands, and Luxembourg). The intention is to create an informal platform for the pharmacometrics community in this region of the world (in industry, academia, hospital pharmacies as well as regulatory bodies), with the goal to promote professional and scientific awareness and interactions. This event was made possible by the combined efforts of the departments of Clinical Pharmacy and Pharmacology and Anaesthesiology and the PKPD Platform of GUIDE / GRIP.

The symposium and pre-symposium workshop will be held Thursday the 29th of March 2018 at the UMCG (Onderwijscentrum, winkelstraat 1). There is no registration fee, but registration is required for participation. Please use the following links to register separately for the symposium and/or pre-symposium workshop, before March 23rd.

Information on how to get there can be found here​.

Pre-symposium workshop: Advancement in Pharmacometric Tools

​​08:30 - 09:00​Arrival
​09:00 – 09:45​​Modeling and simulation in MW-Pharm++ and Edsim++
Nieko Punt (Medimatics) 
​09:45 – 10:30​Simulation (RxODE) and parameter estimation in nlmixr
Rik Schoemaker (Occams) ​
​10:30 – 10:45​Coffee/tea break
​10:45 – 11:30​Climbing Mount Improbable: A comparison of population estimation methods for pharmacometrics
Douglas Eleveld (UMCG)
​11:30 – 12:15​Kernel-Based Visual Hazard Comparison; the alternative for VPCs in RTTE model evaluation
Bas Goulooze (LACDR)​

​Symposium: Data Analysis in Adjacent Areas

​​12:00 – 13:00 ​Arrival and light lunch
​13:00 – 13:15
Jasper Stevens (UMCG)
​13:15 – 14:15​Key note lecture; Mathematical modeling of pharmaco-economic analyses
Maarten Postma (RuG/UMCG)
​14:15 – 14:45​Pharmacokinetic modeling of PET imaging
David Vállez García (UMCG)
14:45 – 15:15
Improving the prediction of local drug distribution in the brain by using partial differential equations
Vivi Rottschäfer, (LU)
​15:15 – 15:45​Coffee Break
​15:45 – 16:15​Capturing the pulsatility of growth hormone secretion in a semi-mechanistic model
Michiel van Esdonk (CHDR/LACDR)
16:15 – 16:45​Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies​
Roeland Wasmann (Radboud UMC)
​16:45 – 17:15​Panel Discussion
​17:15 – 19:00​​Closure followed by reception